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        <identifier>oai:researchdata.se:2020-43-1/1</identifier>
        <datestamp>2026-04-08</datestamp>
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        <setSpec>subject:ssif:30202</setSpec>
        <setSpec>subject:ssif:30209</setSpec>
        <setSpec>subject:ssif:302</setSpec>
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        <setSpec>principal:slug:karolinska-institutet</setSpec>
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        <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
          <dc:type>info:eu-repo/semantics/other</dc:type>
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          <dc:identifier>https://doi.org/10.5878/wh80-0w17</dc:identifier>
          <dc:title xml:lang="en">Rotational Thromboelastometry predicts care level in COVID-19</dc:title>
          <dc:title xml:lang="sv">Rotational Thromboelastometry predicerar vårdnivå vid COVID-19</dc:title>
          <dc:creator>https://orcid.org/0000-0002-5576-5129</dc:creator>
          <dc:creator>https://orcid.org/0000-0002-7403-4305</dc:creator>
          <dc:contributor>Jonas Svensson</dc:contributor>
          <dc:subject xml:lang="en">Anesthesiology and Intensive Care</dc:subject>
          <dc:subject xml:lang="sv">Anestesi och intensivvård</dc:subject>
          <dc:subject xml:lang="en">Hematology</dc:subject>
          <dc:subject xml:lang="sv">Hematologi</dc:subject>
          <dc:subject xml:lang="en">Infectious Medicine</dc:subject>
          <dc:subject xml:lang="sv">Infektionsmedicin</dc:subject>
          <dc:description xml:lang="en">The objective of the study was to test whether Rotational Thromboelastometry (ROTEM) indicate hypercoagulopathy at hospitalization of COVID-19 patients, and whether patients with severe disease have a more pronounced hypercoagulopathy compared with less severely ill patients. 

The study was designed as a prospective observational study where COVID-19 positive patients over 18 years admitted to Capio St Göran’s Hospital in Stockholm, Sweden, were eligible for inclusion. Patients were divided into two groups depending on care level: 1) regular wards (40 patients) or 2) wards with specialized ventilation support (20 patients). ROTEM and other coagulation tests (see table for a list and explanation of variables) was taken after admission and the data were compared with ROTEM in healthy controls.

Conclusion
ROTEM variables (EXTEM-MCF, FIBTEM-MCF, EXTEM-CT, EXTEM-CFT) were significantly different in COVID-19 patients early after admission compared with healthy controls. This pattern was more pronounced in patients with increased disease severity, suggesting that ROTEM-analysis could be a potentially useful predictor of thromboembolic complications and mortality in these patients. 

For details, see publication at: https://doi.org/10.1007/s11239-020-02312-3</dc:description>
          <dc:description xml:lang="sv">Syftet med studien var att testa om Rotational Thromboelastometry (ROTEM) indikerar att patienter med COVID-19 är benägna att bilda blodproppar. Även om provet skiljer sig åt beroende på om patienter på vanlig vårdavdelning testas jämfört med patienter på mer avancerade vårdavdelningar.

Se utförligare beskrivning i den engelska versionen av katalogposten.

För detaljer se artikeln: https://doi.org/10.1007/s11239-020-02312-3</dc:description>
          <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
          <dc:rights>https://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
          <dc:publisher xml:lang="en">Karolinska Institutet</dc:publisher>
          <dc:publisher xml:lang="sv">Karolinska Institutet</dc:publisher>
          <dc:date>2020-08-24T05:49:18.338287Z</dc:date>
          <dc:language>eng</dc:language>
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