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        <identifier>oai:researchdata.se:2022-112-1/2</identifier>
        <datestamp>2026-10-05</datestamp>
        <setSpec>subject:ssif:30110</setSpec>
        <setSpec>subject:ssif:301</setSpec>
        <setSpec>subject:ssif:3</setSpec>
        <setSpec>principal:slug:university-of-gothenburg</setSpec>
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        <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
          <dc:type>info:eu-repo/semantics/other</dc:type>
          <dc:type>http://purl.org/dc/dcmitype/Dataset</dc:type>
          <dc:identifier>https://doi.org/10.5878/ayae-p143</dc:identifier>
          <dc:title xml:lang="en">A landscape of X-inactivation during human T-cell development in the thymus</dc:title>
          <dc:title xml:lang="sv">X-inaktivering under T-cellsutvecklingen i thymus</dc:title>
          <dc:creator>https://orcid.org/0000-0002-4506-9955</dc:creator>
          <dc:contributor>0000-0001-5853-1769</dc:contributor>
          <dc:subject xml:lang="en">Immunology in the Medical Area</dc:subject>
          <dc:subject xml:lang="sv">Immunologi inom det medicinska området</dc:subject>
          <dc:description xml:lang="en">The aim of the study was to investigate X-inactivation during human T-cell development in the thymus. Thymocytes from six different developmental stages from nine individuals were isolated and studied regarding gene expression. The data set contains data from RNA sequencing, DNA methylation and whole exome sequencing.

The dataset contains data from the manuscript "A landscape of X-inactivation during human T-cell development in the thymus" by Gylemo et al, and consists of results from RNA sequencing (fastq.gz), analysis of DNA methylation (Grn.idat), Smart-seq2 single-cell RNA sequencing (fastq.gz) and whole exome DNA sequencing (fastq.gz) of six developmental stages of thymocytes from nine individuals.

The data is described on individual and cell-type level in the tab-separated metadata files (.tsv).
MD5 checksums for each file are included.</dc:description>
          <dc:description xml:lang="sv">Huvudsyftet med studien har varit att studera X-inaktivering under T-cellsutveckling i human thymus. I studien har sex olika utvecklingsstadier av thymocyter isolerats från nio individer och studerats avseende genuttryck. Datamaterialet innehåller data från RNA-sekvensering, DNA-metylering och helexom-sekvensering av DNA.

Datasetet innehåller data från manuskriptet "A landscape of X-inactivation during human T-cell development in the thymus" av Gylemo et al och innehåller resultat från RNA-sekvensering (fastq.gz), analys av DNA-metylering (Grn.idat), Smart-seq2 single-cell RNA sekvensering (fastq.gz) och DNA-exomsekvensering (fastq.gz) av sex olika mognadsstadier av thymocyter från totalt nio individer. 

Data är beskrivna på individ- och celltypsnivå i de bifogade tabbseparerade metadatafilerna (.tsv).
Kontrollsummor i MD5-format för datafilerna finns tillgängliga.</dc:description>
          <dc:rights>info:eu-repo/semantics/restrictedAccess</dc:rights>
          <dc:coverage>SE</dc:coverage>
          <dc:publisher xml:lang="en">University of Gothenburg</dc:publisher>
          <dc:publisher xml:lang="sv">Göteborgs universitet</dc:publisher>
          <dc:date>2024-10-03T08:48:46.542784Z</dc:date>
          <dc:language>eng</dc:language>
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