2026-10-11 https://api.researchdata.se/oai-pmh

oai:researchdata.se:2023-227/1 2026-03-19 subject:ssif:1 subject:ssif:106 subject:ssif:10604 subject:ssif:10609 subject:ssif:10610 subject:ssif:30202 subject:ssif:30112 subject:ssif:301 subject:ssif:302 subject:ssif:3 principal:slug:karolinska-institutet

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.48723/n8wy-bb08 Colony whole genome sequencing of hematopoietic stem and progenitor cell-derived colonies from 2 dual SF3B1-mutant MDS-RS patients Colony whole genome sequencing of hematopoietic stem and progenitor cell-derived colonies from 2 dual SF3B1-mutant MDS-RS patients https://orcid.org/0000-0002-0493-5394 https://orcid.org/0000-0002-7839-3743 Seishi Ogawa Yasuhito Nannya Natural Sciences Naturvetenskap Biological Sciences Biologi Cell Biology Cellbiologi Genetics and Genomics Genetik och genomik Bioinformatics and Computational Biology Bioinformatik och beräkningsbiologi Hematology Hematologi Basic Cancer Research Basal cancerforskning This dataset consists of whole genome sequencing data from single cell-derived colonies obtained through colony-forming assays and culture of FACS-purified hematopoietic stem cells (HSC), multipotent progenitors (MPP), megakaryocyte-erythroid progenitors (MEP) and granulocyte-monocyte progenitors (GMP) from 2 MDS-RS patients, each with 2 competing SF3B1-mutant clones. The objective of this data collection was to assess the clonal hierarchy and history of the SF3B1 mutations. The dataset is approximately 1.2 GB and has filetypes zip, txt, phy and ojb. Denna datauppsättning består av helgenomsekvenseringsdata från kolonier erhållna genom kolonibildande analyser och cellodling av FACS-renade hematopoetiska stamceller (HSC), multipotenta progenitorer (MPP), megakaryocyt-erytroida progenitorer (MEP) och granulocyt-monocytprogenitorer (GMP) ) från 2 MDS-RS-patienter, var och en med 2 konkurrerande SF3B1-mutantkloner. Syftet med denna datainsamling var att bedöma den klonala hierarkin och historien för SF3B1-mutationerna. info:eu-repo/semantics/restrictedAccess https://creativecommons.org/licenses/by-nc-nd/4.0/ Karolinska Institutet Karolinska Institutet 2024-04-18T13:28:56.573715Z eng