2026-10-12 https://api.researchdata.se/oai-pmh

oai:researchdata.se:2024-400/1 2025-07-04 subject:ssif:10203 subject:ssif:10610 subject:ssif:30207 subject:ssif:30226 subject:ssif:102 subject:ssif:106 subject:ssif:302 subject:ssif:1 subject:ssif:3 principal:slug:linkoping-university

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.48360/jcps-gw67 Data for: Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis Data for: Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis Mika Gustafsson https://orcid.org/0000-0001-9456-2044 https://orcid.org/0000-0002-2938-1877 Specific diseases, disorders and medical conditions Specifika sjukdomar, störningar och medicinska tillstånd Bioinformatics (Computational Biology) Bioinformatik (beräkningsbiologi) Bioinformatics and Computational Biology Bioinformatik och beräkningsbiologi Neurology Neurologi Autoimmunity and Inflammation Autoimmunitet och inflammation The concentration of 1463 proteins were measured using the Olink Explore platform which uses Proximity Extension Assay (PEA) technology. The proteins are preselected from four Olink panels: Explore 384 Cardiometabolic, Explore 384 Inflammation, Explore 384 Neurology, and Explore 384 Oncology. The protein concentrations are given as Olink’s relative protein quantification unit on log2 scale: Normalized Protein Expression (NPX). The NPX values were intensity normalized by Olink. Protein levels were measured in cerebrospinal fluid samples (n = 186) and plasma samples (n = 165) from persons with multiple sclerosis and healthy controls. The dataset was originally published in DiVA and moved to SND in 2024. Koncentrationen av 1463 proteiner mättes med hjälp av Olink Explore-plattformen som använder Proximity Extension Assay (PEA) teknologi. Proteinerna är förvalda från fyra Olink-paneler: Explore 384 Cardiometabolic, Explore 384 Inflammation, Explore 384 Neurology och Explore 384 Oncology. Proteinernas koncentrationer anges som Olinks relativa proteinmängdsenhet på log2-skalan: Normalized Protein Expression (NPX). NPX-värdena normaliserades (intensity normalization) av Olink. Proteinhalten mättes i ryggvätskeprov (n = 186) och plasmaprov (n = 165) från personer med multipel skleros och friska kontroller. Datasetet publicerades ursprungligen i DiVA och flyttades till SND 2024. info:eu-repo/semantics/restrictedAccess Linköping University Linköpings universitet 2023-09-22T00:00:00Z eng