2026-10-06 https://api.researchdata.se/oai-pmh

oai:researchdata.se:2026-47/1 2026-09-30 subject:ssif:10203 subject:ssif:10609 subject:ssif:10610 subject:ssif:30107 subject:ssif:30108 subject:ssif:30203 subject:ssif:30112 subject:ssif:10616 subject:ssif:102 subject:ssif:106 subject:ssif:301 subject:ssif:302 subject:ssif:1 subject:ssif:3 principal:slug:karolinska-institutet

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.48723/gr42-ja30 Data for: Principles of subclonal gene dosage across human cancers Data för: Principles of subclonal gene dosage across human cancers https://orcid.org/0000-0001-7462-0278 https://orcid.org/0000-0001-8748-8931 Karolinska Institutet Biotechnology Bioteknik Bioinformatics (Computational Biology) Bioinformatik (beräkningsbiologi) Genetics and Genomics Genetik och genomik Bioinformatics and Computational Biology Bioinformatik och beräkningsbiologi Medical Genetics and Genomics Medicinsk genetik och genomik Cell and Molecular Biology Cell- och molekylärbiologi Cancer and Oncology Cancer och onkologi Basic Cancer Research Basal cancerforskning Molecular Biology Molekylärbiologi The data shared here are joint single-cell Whole genome sequencing (WGS) and single-cell mRNA sequencing from primary patient material from different cancer types. Primary samples from pediatric acute lymphoblastic leukemias, acute myeloid leukemias, breast cancers, melanomas and sarcomas were processed using Direct nuclear tagmentation and RNA-sequencing (DNTR-seq). For more information on DNTR-seq, see ‘A Highly Scalable Method for Joint Whole-Genome Sequencing and Gene-Expression Profiling of Single Cells’, DOI:10.1016/j.molcel.2020.09.025. Data shared here are the fastq files of all single cells sequenced in this study (21826 read 1 and 21826 read 2 files). The size of the dataset is approximately 2 TB. De data som delas här är kombinerad single-cell Whole genome sequencing (WGS) och single-cell mRNA-sekvensering från primärt patientmaterial från olika cancertyper. Primära prover från pediatriska akuta lymfoblastiska leukemier, akuta myeloiska leukemier, bröstcancer, melanom och sarkom bearbetades med Direct nuclear tagmentation and RNA-sequencing (DNTR-seq) För mer detaljerad information om DNTR-seq se ‘A Highly Scalable Method for Joint Whole-Genome Sequencing and Gene-Expression Profiling of Single Cells’, DOI:10.1016/j.molcel.2020.09.025. Data som delas här är fastq-filerna för alla enskilda celler som sekvenserades i denna studie (21826 read 1 och 21826 read 2 filer). Datasetet storlek är ca 2 TB. info:eu-repo/semantics/restrictedAccess SE Karolinska Institutet Karolinska Institutet 2026-09-30T13:16:42.181717Z eng