2026-10-13 https://api.researchdata.se/oai-pmh

oai:researchdata.se:doi-10-17044-scilifelab-21953117/0 2023-05-30 subject:ssif:3 subject:ssif:10609 subject:ssif:106 subject:ssif:1 principal:slug:lund-university

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.17044/SCILIFELAB.21953117 Timing chromosomal amplification events using patterns of somatic mutations in high hyperdiploid acute lymphoblastic leukemia Eleanor Woodward https://orcid.org/0000-0002-3324-1498 https://orcid.org/0000-0001-9063-5592 https://orcid.org/0000-0001-9787-8597 Rebeqa Gunnarsson Linda Olsson Arvidsson https://orcid.org/0000-0001-8403-474X Anders Castor https://orcid.org/0000-0002-3927-1022 https://orcid.org/0000-0002-1639-7124 Jan Zuna Bertil Johansson Floris Foijer Kajsa Paulsson Medical and Health Sciences Medicin och hälsovetenskap Genetics and Genomics Genetik och genomik This dataset included 22 patients with high hyperdiploid acute lymphoblastic leukemia (ALL) collected from the Division of Clinical Genetics, Lund University, Sweden. All samples were subjected to whole genome sequencing by the Illumina HiSeqX platform. Paired-end sequencing (2x150bp) was done to ~60x coverage for diagnostic samples and ~30x coverage for remission. The paired-end reads were aligned to the human reference genome GRCh37 (https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.25/) by the Burrows-Wheeler Aligner tool (version 0.7.17). Duplicate reads marking and local realignment were performed by GATK (version 4.0.11.0). Somatic variants were identified by the GDC DNA-Seq analysis pipeline (Zhang et al.,2021). The data was stored in vcf format and the interpretation of the file is available at: https://docs.gdc.cancer.gov/Data/File_Formats/VCF_Format/. https://creativecommons.org/licenses/by-nc-nd/4.0/ Lund University Lunds universitet 2023-02-02T00:00:00Z