2026-10-14 https://api.researchdata.se/oai-pmh

oai:researchdata.se:doi-10-17044-scilifelab-26064754/0 2024-07-08 subject:ssif:3 subject:ssif:30203 subject:ssif:302 subject:ssif:106 subject:ssif:1 principal:slug:lund-university

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.17044/SCILIFELAB.26064754 The genomic landscape of relapsed infant and childhood KMT2A-rearranged acuteleukemia https://orcid.org/0000-0002-9235-1953 Anna Hagström Andersson Louise Ahlgren Helena Sturesson https://orcid.org/0000-0002-2761-7102 Guangchun Song Michael P. Walsh https://orcid.org/0000-0002-3324-1498 Anders Castor Cornelis Jan Pronk Huanbin Zhao Maud Maillard https://orcid.org/0000-0001-9740-6522 Birgitte Lausen Pauline Schneider https://orcid.org/0000-0003-3185-2962 Katja Pokrovskaja-Tamm Jonas Abrahamsson https://orcid.org/0000-0001-9195-0797 Linda Fogelstrand Pablo Menendez Rob Pieters Jun J. Yang Jinghui Zhang Karin Lindkvist-Petersson Ronald W. Stam Jing Ma Medical and Health Sciences Medicin och hälsovetenskap Cancer and Oncology Cancer och onkologi Biological Sciences Biologi This dataset includes whole genome and whole exome sequencing of diagnostic, germline, and relapse samples of 21 infants and 12 children with relapsed ALL (n=21) or AML (n=12), and targeted deep sequencing of 258 samples taken during treatment for 30 infants or children with ALL or AML. All patients had an underlying rearrangement of the KMT2A gene Whole genome and exome sequencing was performed using Illumina TruSeq Nano protocol. Targeted sequencing libraries was prepared using Nextera XT DNA Sample Preparation Kit (Illumina) and sequenced on the Illumina MiSeq. info:eu-repo/semantics/restrictedAccess Lund University Lunds universitet 2024-07-08T00:00:00Z