2026-10-11 https://api.researchdata.se/oai-pmh

oai:researchdata.se:doi-10-17044-scilifelab-28033793/0 2025-10-02 subject:ssif:3 subject:ssif:30203 subject:ssif:302 principal:slug:lund-university

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.17044/SCILIFELAB.28033793 Single-cell RNA sequencing data from: Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia Carl Sandén https://orcid.org/0000-0001-8703-1173 Thoas Fioretos Medical and Health Sciences Medicin och hälsovetenskap Cancer and Oncology Cancer och onkologi This dataset includes single-cell RNA sequencing (scRNA-seq) data from co-cultures of primary T cells and the HNT-34 AML (acute myeloid leukemia) cell line after treatment with a SLAMF6 antibody or an isotype-matched control antibody. Libraries were produced using the 10X Genomics Chromium GEM-X Single Cell 5ʹ Reagent Kits v3 and sequenced on an Illumina Novaseq 6000 system (Illumina). The dataset is available as raw sequencing reads (fastq; restricted access) or as an annotated matrix of scRNA count data (h5ad). Published in: Sandén et al, Nature Cancer, 2025: https://www.nature.com/articles/s43018-025-01054-6 https://creativecommons.org/licenses/by-nc-nd/4.0/ Lund University Lunds universitet 2025-07-01T00:00:00Z