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        <datestamp>2025-06-13</datestamp>
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          <dc:title xml:lang="en">The plasma proteome in ANCA-associated vasculitis</dc:title>
          <dc:creator>Johanna Dahlqvist</dc:creator>
          <dc:creator>Erik Hellbacher</dc:creator>
          <dc:subject xml:lang="en">Medical and Health Sciences</dc:subject>
          <dc:subject xml:lang="sv">Medicin och hälsovetenskap</dc:subject>
          <dc:subject xml:lang="en">Autoimmunity and Inflammation</dc:subject>
          <dc:subject xml:lang="sv">Autoimmunitet och inflammation</dc:subject>
          <dc:description xml:lang="en">ANCA-associated vasculitides (AAV) are rare but severe disorders. Little is known about the pathophysiology of AAV. In this study, we analyzed the relative levels of 181  proteins using proximity extension assay (Olink) in plasma samples from patients with active AAV (n=66),  matched population  controls (n=138) and disease controls with rheumatoid arthritis (n=31) and systemic lupus erythematosus n=14), respectively. Distinct sets of upregulated proteins were identified in subgroups of patients with AAV defined by ANCA (PR3-ANCA and MPO-ANCA, respectively) compared with controls.</dc:description>
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