2026-10-10 https://api.researchdata.se/oai-pmh

oai:researchdata.se:doi-10-17045-sthlmuni-22555525/0 2025-06-12 subject:ssif:10408 subject:ssif:104 subject:ssif:1 principal:slug:stockholm-university

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.17045/STHLMUNI.22555525 Supplementary Fig. 5c & 6b | Western blots of FUS and TARDBP in iPSC lysates https://orcid.org/0000-0003-4505-9068 Jonas Mechtersheimer Marc-David Ruepp Stefan Reber Biochemistry Biokemi This item is part of the Figshare Project: Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution (https://su.figshare.com/projects/Early_mitochondrial_dysfunction_revealed_across_FUS-_and_TARDBP-ALS_at_single_cell_resolution/163252) From Data Availability Statement for the forthcoming paper in Nature Communications entitled: Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS "We have deposited all raw and processed RNA sequencing data generated in this study on the NCBI Gene Expression Omnibus (GEO) under the accession number GSE226482. The C9orf72-ALS bulk RNA sequencing data was retrieved directly from the authors of the study. [Items under this Figshare Project contain:] "Scans of fluorescent western blots, raw imaging files from confocal microscopy, the analysis files from Opera Phenix, qPCR data sets, and Seahorse assay result files." -------------------------------------------- [Item specific description:] This data belong to Supplementary Fig. 5 and 6. Western blots in iPSC lines with various FUS and TARDBP M337V mutations for FUS and TDP-43 protein expression. The assembled western blots are presented in the PPTX file. The fluorescent signal were scanned on a Odyssey CLx scanner (LI-COR) and exported as Image Studio ZIP archives. More information about the Image Studio software can be obtained here: https://www.licorbio.com/image-studio The raw images are given as TIF files, thumbnails as PNG, and aquisition meta information as TXT files within the exported archives. https://creativecommons.org/licenses/by/4.0/ Stockholm University Stockholms universitet 2025-04-28T00:00:00Z