2026-10-11 https://api.researchdata.se/oai-pmh

oai:researchdata.se:doi-10-17045-sthlmuni-27952080/0 2025-06-13 subject:ssif:30207 subject:ssif:302 subject:ssif:3 subject:ssif:10604 subject:ssif:106 subject:ssif:1 principal:slug:stockholm-university

info:eu-repo/semantics/other http://purl.org/dc/dcmitype/Dataset https://doi.org/10.17045/STHLMUNI.27952080 Fig. 2b-c | Quantitative immunofluorescence microscopy for intracellular FUS localization in ALS motor neurons https://orcid.org/0000-0003-4505-9068 https://orcid.org/0000-0002-2519-9824 https://orcid.org/0000-0003-3264-9800 Neurology Neurologi Cell Biology Cellbiologi This item is part of the Figshare Project: Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution From Data Availability Statement for the paper in Nature Communications entitled: Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS "We have deposited all raw and processed RNA sequencing data generated in this study on the NCBI Gene Expression Omnibus (GEO) under the accession number GSE226482. The C9orf72-ALS bulk RNA sequencing data was retrieved directly from the authors of the study. [Items under this Figshare Project contain:] "Scans of fluorescent western blots, raw imaging files from confocal microscopy, the analysis files from Opera Phenix, qPCR data sets, and Seahorse assay result files." ------------------------- [Item specific description:] Quantititative fluorescene microscopy for FUS protein in ALS motor neurons The dataset are Harmony archives for the high content imager Opera Phenix (Perkim Elmer). The proprietary harmony software creates a database with file organization stored in xml and oar files and folders with raw tif files. More information here on our imaging platform: https://www.kclwcic.co.uk/operaphenix These archives contain thousands of tif files. Therefore, they are compressed into tar.gz files with matching md5 checksums for verification. The prism file is just a graphpad prism file with the summary data. More info here: https://www.graphpad.com/features https://creativecommons.org/licenses/by/4.0/ Stockholm University Stockholms universitet 2025-04-10T00:00:00Z