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        <datestamp>2019-01-29</datestamp>
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          <dc:title xml:lang="en">dN/dS calculation of Thermus virus NrdJm evolution</dc:title>
          <dc:creator>https://orcid.org/0000-0002-8779-6464</dc:creator>
          <dc:creator>Christoph Loderer</dc:creator>
          <dc:creator>Karin Holmfeldt</dc:creator>
          <dc:subject xml:lang="en">Bioinformatics (Computational Biology)</dc:subject>
          <dc:subject xml:lang="sv">Bioinformatik (beräkningsbiologi)</dc:subject>
          <dc:subject xml:lang="en">Bioinformatics and Computational Biology</dc:subject>
          <dc:subject xml:lang="sv">Bioinformatik och beräkningsbiologi</dc:subject>
          <dc:subject xml:lang="en">Evolutionary Biology</dc:subject>
          <dc:subject xml:lang="sv">Evolutionsbiologi</dc:subject>
          <dc:subject xml:lang="en">Biochemistry</dc:subject>
          <dc:subject xml:lang="sv">Biokemi</dc:subject>
          <dc:description xml:lang="en">A log ratio test of significant overrepresentation of non-synonymous to silent (dN/dS) was estimated with codonml from PAML (Yang 1997, https://doi.org/10.1093/bioinformatics/13.5.555 ; Yang 2007, https://doi.org/10.1093/molbev/msm088) by running the program with a fixed and free dN/dS respectively, and the branch leading to the two Thermus virus sequences (marked with “#1” in reftree.newick) designated as the “foreground” branch in the free dN/dS run. This analysis was performed on the Thermus virus/Firmicutes subtree in https://doi.org/10.17045/sthlmuni.7117430.v2, using the same alignment as for the full tree, reverse translated into nucleotides. We could not find correct gene sequences for seven taxa (RefSeq accession numbers: WP_102410887, WP_033167051, WP_054955013, WP_065068364, WP_088370373, WP_087372021, WP_093315575), so they were left out of the analysis.
Scripts in files ending with .codeml; output in .codeml.out files.</dc:description>
          <dc:rights>https://creativecommons.org/licenses/by/4.0/</dc:rights>
          <dc:publisher xml:lang="en">Stockholm University</dc:publisher>
          <dc:publisher xml:lang="sv">Stockholms universitet</dc:publisher>
          <dc:date>2019-01-29T00:00:00Z</dc:date>
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